CJC-1295 no DAC
Original price was: $70.00.$65.00Current price is: $65.00.
CJC-1295 without DAC (also known as Mod GRF 1-29) is a synthetic 30-amino-acid analog of growth hormone-releasing hormone (GHRH), modified at four positions for enhanced enzymatic stability without the Drug Affinity Complex. Extensively studied in preclinical research for its role in pulsatile GH release, typically in combination with GHRP-class peptides. Lyophilized powder, ≥99% purity, third-party tested. For laboratory and research use only — not for human consumption.
| Peptide Family | GHRH Analog |
|---|---|
| Research Application | Tissue Repair Research |
| Strength | 5 MG |
CJC-1295 without DAC (Mod GRF 1-29) — Short-Acting GHRH Analog Research Peptide
CJC-1295 without DAC, also known as Modified GRF 1-29 (Mod GRF 1-29), is a synthetic 30-amino-acid analog of human growth hormone-releasing hormone (GHRH). The compound is modified at four positions to enhance resistance to enzymatic degradation, but does not carry the Drug Affinity Complex (DAC) found in the longer-acting CJC-1295 variant. This shorter-acting profile makes it one of the most extensively researched GHRH analogs for combined-pathway investigations with growth hormone-releasing peptides (GHRPs) such as Ipamorelin.
Mechanism of Action
CJC-1295 without DAC has been investigated in published research for activity across several biological pathways, including:
- GHRH receptor agonism — binding to the GHRH receptor in the anterior pituitary
- Pulsatile GH secretion — research on amplitude-modulated, physiologically pulsatile growth hormone release patterns
- IGF-1 pathway research — downstream insulin-like growth factor-1 signaling
- Synergistic GHRH/GHRP research — investigations into combined GHRH-analog and GHRP-pathway activation kinetics
- Comparative pharmacokinetic research — comparative studies against CJC-1295 with DAC and other GHRH analogs
The defining feature of CJC-1295 without DAC in research literature is its shorter half-life of approximately 30 minutes, compared to roughly 6–8 days for CJC-1295 with DAC. This shorter window of activity is better aligned with the natural pulsatile release pattern of growth hormone, which has made it a preferred research tool for investigating physiologically-modeled GH release kinetics when paired with a GHRP.
CJC-1295 Without DAC vs. With DAC
Two distinct versions of CJC-1295 are commonly available in research peptide literature:
- CJC-1295 without DAC (this product, also known as Mod GRF 1-29): shorter half-life (~30 minutes), typically used in research paired with GHRPs such as Ipamorelin for pulsatile GH release investigations that more closely mirror endogenous secretion patterns
- CJC-1295 with DAC: extended half-life (~6–8 days) via albumin binding, used in research on sustained GHRH-receptor activation over multi-day windows
The two are distinct compounds with different research applications. Researchers should select the version appropriate for the specific research model being investigated.
Research Applications
CJC-1295 without DAC is widely used in research contexts including:
- Pulsatile GH release research models
- Combined GHRH-analog and GHRP-pathway research (typically with Ipamorelin, GHRP-2, or GHRP-6)
- IGF-1 response and downstream signaling research
- Comparative analysis against CJC-1295 with DAC, Sermorelin, and Tesamorelin
- Pharmacokinetic research on short-acting GHRH analogs
- Body composition and metabolic research using physiologically-modeled GH-axis stimulation
Product Specifications
- Compound: CJC-1295 without DAC (Mod GRF 1-29)
- Form: Lyophilized white powder
- Purity: ≥99% (verified by HPLC and mass spectrometry)
- Available sizes: 10mg
- Third-party tested: Certificate of Analysis available on request
Reconstitution & Storage
Lyophilized CJC-1295 without DAC should be stored at -20°C for long-term stability and protected from light. Once reconstituted with bacteriostatic water, the solution should be refrigerated at 2–8°C and used within the timeframe indicated on the product COA. Avoid repeated freeze-thaw cycles, as they can degrade peptide integrity.
Shipping & Handling
All orders are shipped with temperature-controlled packaging to preserve peptide integrity. Domestic orders typically arrive within 2–4 business days. Tracking is provided on every order.
Important Disclaimer
This product is sold strictly for laboratory research and in-vitro use only. It is not intended for human or animal consumption, diagnostic use, therapeutic use, or any form of clinical application. By purchasing, you confirm that you are a qualified researcher or affiliated with a licensed research institution and that this product will be handled in accordance with all applicable laws and safety standards.
CJC-1295 without DAC is not approved by the FDA for human use, and this product is not a substitute for any prescribed medication.
Domestic Shipping (Canada)
We ship Canada-wide using Canada Post Xpresspost with full tracking provided on every shipment.
Standard delivery: 2-5 business days nationwide
Free shipping on orders over $200 CAD
Discreet, unmarked packaging on all orders
Tracking number provided via email upon dispatch
Storage & Handling
Proper storage and handling are essential to maintaining peptide stability and ensuring the integrity of your research material.
Storage Recommendations
Lyophilized peptides should be stored at -20°C for long-term preservation. For short-term storage of up to 30 days, refrigeration between 2-8°C is acceptable. Reconstituted peptides should always be refrigerated and used within 30 days.
Avoid the following:
Direct sunlight or UV exposure Repeated freeze-thaw cycles Temperature fluctuations Storage at room temperature beyond brief handling periods
Reconstitution Best Practices
Allow vials to reach room temperature before opening to prevent condensation. Use bacteriostatic water as the diluent for most peptides, injecting slowly along the side of the vial. Gently swirl to dissolve — do not shake. Allow the solution to fully dissolve before drawing for research use.
Shelf Life
Lyophilized peptides maintain potency for up to 24 months when stored properly at -20°C. Reconstituted solutions should be used within 30 days for optimal research results.
Research Use Only
All products supplied by Kinetic Compounds are intended strictly for in-vitro laboratory research and development purposes.
Intended Use
These compounds are designed exclusively for qualified researchers and research institutions conducting laboratory studies. All products are research-grade and may not have been evaluated by the FDA for human use.
Prohibited Uses
Our products are NOT approved for:
Human consumption or administration Veterinary or animal use Diagnostic procedures Therapeutic applications Cosmetic application Resale for non-research purposes
Buyer Responsibility
By purchasing from Kinetic Compounds, you acknowledge and agree to the following:
You are a qualified researcher or represent a research institution All products will be used solely for in-vitro laboratory research You will handle products in accordance with applicable safety regulations You will not redistribute these compounds for human or animal consumption You assume full responsibility for the proper use and handling of these research materials
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