KPV
$63.00
KPV is a synthetic tripeptide composed of lysine, proline, and valine — the C-terminal fragment of alpha-melanocyte-stimulating hormone (α-MSH). Extensively studied in preclinical research for its role in anti-inflammatory and immune-modulation pathways. Lyophilized powder, ≥99% purity, third-party tested. For laboratory and research use only — not for human consumption.
| Peptide Family | Anti-Inflammatory Peptide |
|---|---|
| Research Application | Anti-Inflammatory Research |
| Strength | 10 MG |
KPV — α-MSH Tripeptide Research Peptide
KPV is a synthetic tripeptide composed of three amino acids — lysine (K), proline (P), and valine (V) — corresponding to the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH). Despite its small molecular size, KPV retains a significant portion of the anti-inflammatory activity associated with the parent α-MSH peptide in published research, making it one of the most extensively studied short-chain anti-inflammatory peptides in modern immunology literature.
Mechanism of Action
KPV has been investigated in published research for activity across several biological pathways, including:
- NF-κB pathway modulation — research on the influence of KPV on nuclear factor-kappa B signaling, a central pathway in inflammatory gene expression
- Pro-inflammatory cytokine signaling — investigations into TNF-α, IL-1β, IL-6, and other inflammatory mediator pathways in preclinical models
- Mast cell activity — research on histamine release and mast cell degranulation pathways
- Gastrointestinal inflammation research — studies on intestinal mucosal integrity and colitis research models
- Antimicrobial activity — investigations into direct antimicrobial effects against bacterial and fungal targets
- Wound and tissue repair — research on epithelial repair and inflammatory resolution pathways
Because of its compact tripeptide structure, KPV has been studied across a particularly broad range of delivery contexts in preclinical research, including topical, oral, and systemic models.
Research Applications
KPV is widely used in research contexts including:
- Anti-inflammatory pathway research
- Inflammatory bowel disease and colitis research models
- Dermatological and skin inflammation research
- Mast cell biology and histamine-pathway studies
- Antimicrobial peptide research
- Comparative analysis against α-MSH and other melanocortin-derived peptides
- Innate immunity and cytokine signaling research
Product Specifications
- Compound: KPV (Lys-Pro-Val tripeptide)
- Form: Lyophilized white powder
- Purity: ≥99% (verified by HPLC and mass spectrometry)
- Available sizes: 10mg
- Third-party tested: Certificate of Analysis available on request
Reconstitution & Storage
Lyophilized KPV should be stored at -20°C for long-term stability and protected from light. Once reconstituted with bacteriostatic water, the solution should be refrigerated at 2–8°C and used within the timeframe indicated on the product COA. Avoid repeated freeze-thaw cycles, as they can degrade peptide integrity.
Shipping & Handling
All orders are shipped with temperature-controlled packaging to preserve peptide integrity. Domestic orders typically arrive within 2–4 business days. Tracking is provided on every order.
Important Disclaimer
This product is sold strictly for laboratory research and in-vitro use only. It is not intended for human or animal consumption, diagnostic use, therapeutic use, or any form of clinical application. By purchasing, you confirm that you are a qualified researcher or affiliated with a licensed research institution and that this product will be handled in accordance with all applicable laws and safety standards.
KPV is not approved by the FDA for human use, and this product is not a substitute for any prescribed medication.
Domestic Shipping (Canada)
We ship Canada-wide using Canada Post Xpresspost with full tracking provided on every shipment.
Standard delivery: 2-5 business days nationwide
Free shipping on orders over $200 CAD
Discreet, unmarked packaging on all orders
Tracking number provided via email upon dispatch
Storage & Handling
Proper storage and handling are essential to maintaining peptide stability and ensuring the integrity of your research material.
Storage Recommendations
Lyophilized peptides should be stored at -20°C for long-term preservation. For short-term storage of up to 30 days, refrigeration between 2-8°C is acceptable. Reconstituted peptides should always be refrigerated and used within 30 days.
Avoid the following:
Direct sunlight or UV exposure Repeated freeze-thaw cycles Temperature fluctuations Storage at room temperature beyond brief handling periods
Reconstitution Best Practices
Allow vials to reach room temperature before opening to prevent condensation. Use bacteriostatic water as the diluent for most peptides, injecting slowly along the side of the vial. Gently swirl to dissolve — do not shake. Allow the solution to fully dissolve before drawing for research use.
Shelf Life
Lyophilized peptides maintain potency for up to 24 months when stored properly at -20°C. Reconstituted solutions should be used within 30 days for optimal research results.
Research Use Only
All products supplied by Kinetic Compounds are intended strictly for in-vitro laboratory research and development purposes.
Intended Use
These compounds are designed exclusively for qualified researchers and research institutions conducting laboratory studies. All products are research-grade and may not have been evaluated by the FDA for human use.
Prohibited Uses
Our products are NOT approved for:
Human consumption or administration Veterinary or animal use Diagnostic procedures Therapeutic applications Cosmetic application Resale for non-research purposes
Buyer Responsibility
By purchasing from Kinetic Compounds, you acknowledge and agree to the following:
You are a qualified researcher or represent a research institution All products will be used solely for in-vitro laboratory research You will handle products in accordance with applicable safety regulations You will not redistribute these compounds for human or animal consumption You assume full responsibility for the proper use and handling of these research materials
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