VIP (Vasoactive Intestinal Peptide)
$86.00
VIP (Vasoactive Intestinal Peptide) is a naturally occurring 28-amino-acid neuropeptide first identified in the small intestine. Extensively studied in preclinical research for its role in vasodilation, immune modulation, and neuroprotective pathways. Lyophilized powder, ≥99% purity, third-party tested. For laboratory and research use only — not for human consumption.
| Peptide Family | Anti-Inflammatory Peptide, Neuropeptide |
|---|---|
| Research Application | Anti-Inflammatory Research, Neuroprotection Research |
| Strength | 10 MG |
VIP — Vasoactive Intestinal Peptide Research Compound
VIP (Vasoactive Intestinal Peptide) is a naturally occurring 28-amino-acid neuropeptide first isolated from the small intestine in 1970 and subsequently identified throughout the central nervous system, peripheral nervous system, and immune tissues. VIP belongs to the secretin/glucagon peptide superfamily and is one of the most extensively researched neuropeptides in modern immunology, neurology, and vascular biology literature.
Mechanism of Action
VIP has been investigated in published research for activity across several biological pathways, including:
- VPAC1 and VPAC2 receptor agonism — binding to two distinct G-protein-coupled receptors with broad tissue distribution
- cAMP signaling — activation of adenylate cyclase and downstream cAMP-mediated pathways
- Vasodilation pathways — research on smooth muscle relaxation and vascular tone in preclinical models
- Immune modulation — investigations into T-cell differentiation, macrophage polarization, and cytokine signaling
- Anti-inflammatory signaling — research on pro-inflammatory cytokine suppression including TNF-α, IL-6, and IL-12
- Neuroprotection — studies on neuronal survival and neurodegenerative pathway research models
- Circadian rhythm regulation — research on suprachiasmatic nucleus function and biological-clock pathways
- Bronchodilation and pulmonary research — investigations into airway smooth muscle and respiratory pathway models
VIP is unusual among neuropeptides in that it is studied across an exceptionally broad range of biological systems — vascular, immune, neurological, gastrointestinal, and respiratory — making it a foundational reference compound in multiple research disciplines.
Research Applications
VIP is widely used in research contexts including:
- Vasodilation and vascular tone research
- Immune modulation and autoimmune research models
- Anti-inflammatory pathway studies
- Neuroprotection and neurodegenerative research
- Sarcoidosis and chronic inflammatory research models
- Mast cell activation syndrome (MCAS) research
- Pulmonary and airway smooth muscle research
- Circadian rhythm and suprachiasmatic nucleus studies
- Comparative analysis alongside related peptides such as PACAP
Product Specifications
- Compound: VIP (Vasoactive Intestinal Peptide)
- Form: Lyophilized white powder
- Purity: ≥99% (verified by HPLC and mass spectrometry)
- Available sizes: 10mg
- Third-party tested: Certificate of Analysis available on request
Reconstitution & Storage
Lyophilized VIP should be stored at -20°C for long-term stability and protected from light. Once reconstituted with bacteriostatic water, the solution should be refrigerated at 2–8°C and used within the timeframe indicated on the product COA. VIP is particularly sensitive to enzymatic degradation in solution, so careful handling and avoidance of repeated freeze-thaw cycles is important to preserve peptide integrity.
Shipping & Handling
All orders are shipped with temperature-controlled packaging to preserve peptide integrity. Domestic orders typically arrive within 2–4 business days. Tracking is provided on every order.
Important Disclaimer
This product is sold strictly for laboratory research and in-vitro use only. It is not intended for human or animal consumption, diagnostic use, therapeutic use, or any form of clinical application. By purchasing, you confirm that you are a qualified researcher or affiliated with a licensed research institution and that this product will be handled in accordance with all applicable laws and safety standards.
VIP is not approved by the FDA for human use, and this product is not a substitute for any prescribed medication.
Domestic Shipping (Canada)
We ship Canada-wide using Canada Post Xpresspost with full tracking provided on every shipment.
Standard delivery: 2-5 business days nationwide
Free shipping on orders over $200 CAD
Discreet, unmarked packaging on all orders
Tracking number provided via email upon dispatch
Storage & Handling
Proper storage and handling are essential to maintaining peptide stability and ensuring the integrity of your research material.
Storage Recommendations
Lyophilized peptides should be stored at -20°C for long-term preservation. For short-term storage of up to 30 days, refrigeration between 2-8°C is acceptable. Reconstituted peptides should always be refrigerated and used within 30 days.
Avoid the following:
Direct sunlight or UV exposure Repeated freeze-thaw cycles Temperature fluctuations Storage at room temperature beyond brief handling periods
Reconstitution Best Practices
Allow vials to reach room temperature before opening to prevent condensation. Use bacteriostatic water as the diluent for most peptides, injecting slowly along the side of the vial. Gently swirl to dissolve — do not shake. Allow the solution to fully dissolve before drawing for research use.
Shelf Life
Lyophilized peptides maintain potency for up to 24 months when stored properly at -20°C. Reconstituted solutions should be used within 30 days for optimal research results.
Research Use Only
All products supplied by Kinetic Compounds are intended strictly for in-vitro laboratory research and development purposes.
Intended Use
These compounds are designed exclusively for qualified researchers and research institutions conducting laboratory studies. All products are research-grade and may not have been evaluated by the FDA for human use.
Prohibited Uses
Our products are NOT approved for:
Human consumption or administration Veterinary or animal use Diagnostic procedures Therapeutic applications Cosmetic application Resale for non-research purposes
Buyer Responsibility
By purchasing from Kinetic Compounds, you acknowledge and agree to the following:
You are a qualified researcher or represent a research institution All products will be used solely for in-vitro laboratory research You will handle products in accordance with applicable safety regulations You will not redistribute these compounds for human or animal consumption You assume full responsibility for the proper use and handling of these research materials
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