LL-37

$94.00

LL-37 is a synthetic human cathelicidin-derived peptide composed of 37 amino acids. Extensively studied in preclinical research for its role in antimicrobial activity, immune modulation, and tissue repair pathways. Lyophilized powder, ≥99% purity, third-party tested. For laboratory and research use only — not for human consumption.

Peptide Family
Research Application
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Description

LL-37 — Cathelicidin-Derived Antimicrobial Research Peptide

LL-37 is a synthetic 37-amino acid peptide derived from the C-terminal end of the human cathelicidin antimicrobial protein (hCAP-18). It is the only known cathelicidin-derived peptide expressed in humans and one of the most extensively researched host-defense peptides in modern immunology and microbiology literature.

Mechanism of Action

LL-37 has been investigated in published research for activity across several biological pathways, including:

  • Antimicrobial activity — disruption of bacterial, viral, and fungal membranes in preclinical models
  • Immune modulation — interaction with innate immune signaling and cytokine pathways
  • Chemotaxis — recruitment of immune cells including neutrophils, monocytes, and T-cells in research models
  • Angiogenesis — formation of new blood vessels and capillary networks
  • Wound and tissue repair — research on keratinocyte migration and epithelial repair processes
  • Biofilm research — investigations into bacterial biofilm formation and disruption

Because of its dual role as both a direct antimicrobial agent and an immune modulator in preclinical research, LL-37 has become a foundational reference compound in host-defense peptide literature.

Research Applications

LL-37 is widely used in research contexts including:

  • Antimicrobial and antibacterial pathway studies
  • Innate immunity and host-defense peptide research
  • Wound healing and epithelial repair investigations
  • Biofilm and microbial resistance research models
  • Inflammatory pathway and cytokine signaling studies
  • Comparative analysis against other cathelicidin and defensin-class peptides

Product Specifications

  • Compound: LL-37 (Cathelicidin Antimicrobial Peptide)
  • Form: Lyophilized white powder
  • Purity: ≥99% (verified by HPLC and mass spectrometry)
  • Available sizes: 10mg
  • Third-party tested: Certificate of Analysis available on request

Reconstitution & Storage

Lyophilized LL-37 should be stored at -20°C for long-term stability and protected from light. Once reconstituted with bacteriostatic water, the solution should be refrigerated at 2–8°C and used within the timeframe indicated on the product COA. Avoid repeated freeze-thaw cycles, as they can degrade peptide integrity.

Shipping & Handling

All orders are shipped with temperature-controlled packaging to preserve peptide integrity. Domestic orders typically arrive within 2–4 business days. Tracking is provided on every order.

Important Disclaimer

This product is sold strictly for laboratory research and in-vitro use only. It is not intended for human or animal consumption, diagnostic use, therapeutic use, or any form of clinical application. By purchasing, you confirm that you are a qualified researcher or affiliated with a licensed research institution and that this product will be handled in accordance with all applicable laws and safety standards.

LL-37 is not approved by the FDA for human use, and this product is not a substitute for any prescribed medication.

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Shipping & Delivery

Domestic Shipping (Canada)

We ship Canada-wide using Canada Post Xpresspost with full tracking provided on every shipment.

Standard delivery: 2-5 business days nationwide
Free shipping on orders over $200 CAD
Discreet, unmarked packaging on all orders
Tracking number provided via email upon dispatch

Storage & Handling

Storage & Handling

Proper storage and handling are essential to maintaining peptide stability and ensuring the integrity of your research material.

Storage Recommendations

Lyophilized peptides should be stored at -20°C for long-term preservation. For short-term storage of up to 30 days, refrigeration between 2-8°C is acceptable. Reconstituted peptides should always be refrigerated and used within 30 days.

Avoid the following:

Direct sunlight or UV exposure Repeated freeze-thaw cycles Temperature fluctuations Storage at room temperature beyond brief handling periods

Reconstitution Best Practices

Allow vials to reach room temperature before opening to prevent condensation. Use bacteriostatic water as the diluent for most peptides, injecting slowly along the side of the vial. Gently swirl to dissolve — do not shake. Allow the solution to fully dissolve before drawing for research use.

Shelf Life

Lyophilized peptides maintain potency for up to 24 months when stored properly at -20°C. Reconstituted solutions should be used within 30 days for optimal research results.

Research Disclaimer

Research Use Only

All products supplied by Kinetic Compounds are intended strictly for in-vitro laboratory research and development purposes.

Intended Use

These compounds are designed exclusively for qualified researchers and research institutions conducting laboratory studies. All products are research-grade and may not have been evaluated by the FDA for human use.

Prohibited Uses

Our products are NOT approved for:

Human consumption or administration Veterinary or animal use Diagnostic procedures Therapeutic applications Cosmetic application Resale for non-research purposes

Buyer Responsibility

By purchasing from Kinetic Compounds, you acknowledge and agree to the following:

You are a qualified researcher or represent a research institution All products will be used solely for in-vitro laboratory research You will handle products in accordance with applicable safety regulations You will not redistribute these compounds for human or animal consumption You assume full responsibility for the proper use and handling of these research materials