Pinealon

Pinealon — Khavinson Tripeptide Research Compound

Pinealon is a synthetic tripeptide composed of three amino acids — glutamate, aspartate, and arginine (Glu-Asp-Arg) — developed within the Khavinson peptide research lineage at the St. Petersburg Institute of Bioregulation and Gerontology. The compound was designed as a short peptide bioregulator targeting pineal gland function and was developed in the same research tradition as Epitalon and other Khavinson-family peptides. Pinealon is one of the more extensively researched short peptide bioregulators in the cellular aging and neuroprotection research category.

Mechanism of Action

Pinealon has been investigated in published research for activity across several biological pathways, including:

• Antioxidant pathway activity — research on free radical scavenging and reduction of reactive oxygen species in cellular models
• Apoptosis pathway research — investigations into the influence of Pinealon on programmed cell death pathways in neuronal cell models
• Neuroprotection research — preclinical studies on neuronal survival under conditions of oxidative stress, hypoxia, and hyperhomocysteinemia in research models
• Gene expression modulation — research on Pinealon’s documented activity at gene promoter regions, including epigenetic and chromatin-related mechanisms — a characteristic of the Khavinson short peptide bioregulator class
• Cellular senescence — research on senescence markers and cellular aging pathways in fibroblast and neuronal cell-line models
• Cognitive pathway research — preclinical investigations into learning and memory pathway research models

Pinealon belongs to a broader class of short-chain peptide bioregulators developed within the Khavinson research framework, which posits that short peptides can selectively bind to specific gene promoter regions and influence transcription of associated genes. This proposed mechanism is foundational to the Khavinson peptide research lineage and forms the theoretical basis for much of the published research on these compounds.

Research Applications

Pinealon is widely used in research contexts including:

• Neuroprotection and neurodegenerative research models
• Oxidative stress and antioxidant pathway research
• Cellular senescence and aging research
• Gene expression and epigenetic modulation research
• Cognitive and memory pathway research models
• Comparative analysis alongside other Khavinson peptides such as Epitalon
• Hyperhomocysteinemia and metabolic stress research models

Product Specifications

• Compound: Pinealon
• Sequence: Glu-Asp-Arg (Glutamate-Aspartate-Arginine)
• Form: Lyophilized white powder
• Purity: ≥99% (verified by HPLC and mass spectrometry)
• Available sizes: 10mg
• Third-party tested: Certificate of Analysis available on request

Reconstitution & Storage

Lyophilized Pinealon should be stored at -20°C for long-term stability and protected from light. Once reconstituted with bacteriostatic water, the solution should be refrigerated at 2–8°C and used within the timeframe indicated on the product COA. Avoid repeated freeze-thaw cycles, as they can degrade peptide integrity.

Shipping & Handling

All orders are shipped with temperature-controlled packaging to preserve peptide integrity. Domestic orders typically arrive within 2–4 business days. Tracking is provided on every order.

Important Disclaimer

This product is sold strictly for laboratory research and in-vitro use only. It is not intended for human or animal consumption, diagnostic use, therapeutic use, or any form of clinical application. By purchasing, you confirm that you are a qualified researcher or affiliated with a licensed research institution and that this product will be handled in accordance with all applicable laws and safety standards.

Pinealon is not approved by the FDA for human use, and this product is not a substitute for any prescribed medication.